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Overview:
There are 13 differences and 5 similarities between Intuniv, Kapvay
| Basic Information |
| Generic Name |
| Guanfacine |
Clonidine |
| Class |
| Antiadrenergic Agents, Centrally Acting |
Antiadrenergic Agents, Centrally Acting |
| Prescription Generic Available |
| No |
No |
| Pregnancy cat. |
| B(us) |
C(us) |
| Approved Age |
| 6 And Older |
6 And Older |
| Excretion |
| Renal |
Urinary (40-50%) |
| Possible Side Effects |
| Sleepiness, Headache, Fatigue, Abdominal Pain. Rarely, Intuniv Can Cause Low Blood Pressure And Heart Rhythm Changes. |
Fatigue, Dizziness, Dry Mouth, Irritability, Behavior Problems, Low Blood Pressure. Stopping This Medicine Suddenly Can Result In High Blood Pressure. |
|
| Dosage, Usage and Forms |
| Routes (of administration) |
| Oral |
Oral, Transdermal |
| Dosage |
| 1–4 Mg Daily (do Not Increase
Faster Than 1 Mg/wk) |
|
|
Maximum daily dose |
| 4 mg |
|
| Duration |
| Long-acting |
Long-acting |
|
Duration - time |
| 24 h |
24 h |
| Chemical Data |
| Molecular mass (g/mol) |
| 246.093 G/mol |
230.093 G/mol |
| Half Life |
| 14.8-18.3 Hours |
12-33 Hours |
| Formula |
| C9h9cl2n3o |
C9h9cl2n3 |
| Bioavailability |
| 80-100% |
75-95% |
| Protein binding |
| 70 % |
20-40% |
| Metabolism |
| Hepatic |
Hepatic To Inactive Metabolites |