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Basic Information |
Generic Name |
|
Methylphenidate |
vs |
Lisdexamfetamine |
|
Class |
|
Cns Stimulants |
vs |
Cns Stimulants |
|
Prescription Generic Available |
|
No |
vs |
No |
|
Pregnancy cat. |
|
C(us) |
vs |
C(us) |
|
Approved Age |
|
6 And Older |
vs |
6 And Older |
|
Legal Status |
|
Schedule Ii (us) |
vs |
Pharmacist Only (au) Pom (uk) Schedule Ii (us) |
|
WADA Category |
|
S6 - Stimulants |
vs |
|
|
Dependence Liability |
|
High |
vs |
|
|
Excretion |
|
|
vs |
Renal: ~2% |
|
Possible Side Effects |
|
Skin Irritation, Some Loss Of Appetite, Weight Loss, Sleep Problems, Irritability, Tics. |
vs |
Some Loss Of Appetite, Weight Loss, Sleep Problems, Irritability, Tics. |
|
Dosage, Usage and Forms |
Routes (of administration) |
|
Oral, Transdermal |
vs |
Oral |
|
Dosage |
|
10–30 Mg Q Am |
vs |
30 Mg Q Am–70 Mg Q Am |
|
Maximum daily dose |
|
30 mg |
vs |
70 mg |
|
Duration |
|
Long-acting |
vs |
Long-acting |
|
Duration - time |
|
8-12 H |
vs |
8-12 H |
|
Chemical Data |
Molecular mass (g/mol) |
|
|
vs |
263.378 G/mol |
|
Half Life |
|
3-4 Hours |
vs |
< 1 Hour (prodrug Molecule), 12-13 Hours (d-amphetamine) |
|
Formula |
|
C14h19no2 |
vs |
C15h25n3o |
|
Bioavailability |
|
|
vs |
28 % |
|
Metabolism |
|
Hepatic |
vs |
Gastro-intestinal (initial); Hepatic (extensively Cyp2d6) After Conversion To D-amphetamine |
|
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