Home > ADHD Medications > Comparisons
Compare Adderall XR vs Concerta vs Dextrostat vs Focalin vs Intuniv vs Strattera vs Vyvanse ADHD Medications
Add another Item to this comparison Add Item |
|||||||
| Basic Information | |||||||
|
Generic Name
|
Amphetamine And Dextroamphetamine | Methylphenidate | Dextroamphetamine | Dexmethylphenidate | Guanfacine | Atomoxetine | Lisdexamfetamine |
|
Class
|
Cns Stimulants | Cns Stimulants | Cns Stimulants | Cns Stimulants | Antiadrenergic Agents, Centrally Acting | Cns Stimulants | Cns Stimulants |
|
Prescription Generic Available
|
Yes | Yes | Yes | Yes | No | No | No |
|
Pregnancy cat.
|
C(us) | C(us) | C(us) | C(us) | B(us) | B3(au) C(us) | C(us) |
|
Approved Age
|
3 And Older | 6 And Older | 3 And Older | 6 And Older | 6 And Older | 6 And Older | 6 And Older |
|
Legal Status
|
Schedule Ii (us) | Schedule Ii (us) | Schedule Ii (us) | Schedule Ii (us) | Pharmacist Only (au) Pom (uk) Schedule Ii (us) | ||
|
WADA Category
|
S6 - Stimulants | S6 - Stimulants | |||||
|
Dependence Liability
|
High | High | High | High | |||
|
Excretion
|
Urinary | Urinary | Urinary | Renal | Renal | Renal (>80%) And Fecal ( | Renal: ~2% |
|
Possible Side Effects
|
Some Loss Of Appetite, Weight Loss, Sleep Problems, Irritability, Tics. | Some Loss Of Appetite, Weight Loss, Sleep Problems, Irritability, Tics. | Some Loss Of Appetite, Weight Loss, Sleep Problems, Irritability, Tics. | Some Loss Of Appetite, Weight Loss, Sleep Problems, Irritability, Tics. | Sleepiness, Headache, Fatigue, Abdominal Pain. Rarely, Intuniv Can Cause Low Blood Pressure And Heart Rhythm Changes. | Sleep Problems, Anxiety, Fatigue, Upset Stomach, Dizziness, Dry Mouth. Rarely, Liver Damage | Some Loss Of Appetite, Weight Loss, Sleep Problems, Irritability, Tics. |
|
0Comments
|
|||||||
| Dosage, Usage and Forms | |||||||
|
Routes (of administration)
|
(medical) Oral, Insufflated, Intravenous | Oral | Oral | Oral | Oral | Oral | Oral |
|
Dosage
|
5 Mg Q Am–40 Mg Q Am | 18 Mg Q Am–72 Mg Q Am (if 12+ Y.o.) | 3-5: 2.5mg Qam–20 Mg Bid; 5- 16: 5 Mg Q Am–20 Mg Bid | 2.5 Mg Bid–10 Mg Bid | 1–4 Mg Daily (do Not Increase Faster Than 1 Mg/wk) | 30 Mg Q Am–70 Mg Q Am | |
|
Maximum daily dose
|
40 mg |
72 mg |
20 mg |
10 mg |
4 mg |
70 mg |
|
|
Duration
|
Long-acting | Long-acting | Short-acting | Short-acting | Long-acting | Long-acting | Long-acting |
|
Duration - time
|
10-14 H | 10-16 H | 3-5 H | 3-4 H | 24 h |
24 h |
8-12 H |
| Chemical Data | |||||||
|
Molecular mass (g/mol)
|
135.21 G/mol | 269.77 G/mol | 135.206 G/mol | 233.31 G/mol | 246.093 G/mol | 255.36 G/mol 291.81 G/mol (hydrochloride) | 263.378 G/mol |
|
Half Life
|
10 Hours |
3-5 Hours | 10 Hours |
4 Hours |
14.8-18.3 Hours | 5 Hours |
< 1 Hour (prodrug Molecule), 12-13 Hours (d-amphetamine) |
|
Formula
|
C9h13n | C14h19no2•hcl | (c9h13n)2•h2so4 | C14h19no2 | C9h9cl2n3o | C17h21no | C15h25n3o |
|
Bioavailability
|
Nasal 75%; Rectal 95-99%; Intravenous 100% | 11-52% |
22-25% |
80-100% |
63-94% |
28 % |
|
|
Protein binding
|
15 % |
15 % |
12-15% |
70 % |
40 % |
||
|
Metabolism
|
Hepatic | Hepatic | Hepatic | Hepatic | Hepatic | Hepatic, Via Cyp2d6 | Gastro-intestinal (initial); Hepatic (extensively Cyp2d6) After Conversion To D-amphetamine |
Add Comment about "
Add general comment
cancel